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Many studies have confirmed oxidant-antioxidant imbalance in migraine, including NO, malondialdehyde (MDA), thiobarbituric acid reactive substances, thiol, catalase, superoxide dismutase, and glutathione imbalances (141, 142)

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Key Takeaway IV Glutathione offers direct delivery into the bloodstream, but the cost and commitment of ongoing treatments may make oral or liposomal supplementation a more practical long-term option for many individuals

Here, the first linear discriminant (LD1) is shown

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