how to sleep better on semaglutide and Sleep: What's the Connection? GLP-1 Sleep Issues: Managing Insomnia

18 An even greater weight reduction of 9.6% was achieved with a higher dose of 2.4 mg weekly over 68 weeks in a trial in adults with overweight or obesity and diabetes

Here's the catch: your body's natural GLP-1 has an extremely short lifespan

The results will appear gradually over 1-3 weeks

Research has shown that individuals with higher glutathione levels demonstrate better preservation of muscle mass, cognitive function, immune competence, and physical endurance as they age

If you want to use both, consider alternating nights [6]

So the benefit is real, but it is indirect and it depends on whether you were low to begin with