Retatrutide, also known as LY3437943 or LY-3437943, is a synthetic research peptide studied for activity across the glucagon, GIP, and GLP-1 receptor pathways
When you eat, GLP-1 triggers your body to produce insulin to lower your blood sugar and sends signals to your brain that youre full
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For others, side effects can interfere with daily life
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Unlike earlier single or dual incretin-based therapies, Retatrutide is known as a triple hormone receptor agonist, acting simultaneously on GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon receptors