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It induces lipolysis (fat breakdown) in adipose tissue, increasing the production of free fatty acids and ketone bodies

SH2B1 defends against energy imbalance, obesity, and metabolic disease via a paraventricular hypothalamusdorsal raphe nucleus neurocircuit

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Sposito was supported by a fellowship grant of productivity in research from Brazilian National Research Council (CNPq) (grant number 300313/2007-1)

Studies have found that people who used tirzepatide injections such as Zepbound lost more weight and were more likely to reach specific weight loss targets than those using semaglutide medications such as Wegovy