Toxins (Basel) 12 (4), 245
Glutathione might inhibit the effects of cerebral infarction and enhance antiapoptotic signaling after ischemic stroke, suggesting that GSH may be a potent therapeutic antioxidant that can attenuate severe pathologies after ischemic stroke, and stimulating GSH synthesis through administration of GSH precursors and micronutrients like selenium can optimize GSH and GSH peroxidase for optimal antioxidant defense in cerebral ischemia (155, 156)
strong depolarization of the post-synaptic cell completely displaces the magnesium ions that block NMDA ion channels and allows calcium ions to enter a cell probably causing LTP, while weaker depolarization only partially displaces the Mg 2+ ions, resulting in less Ca 2+ entering the post-synaptic neuron and lower intracellular Ca 2+ concentrations (which activate protein phosphatases and induce long-term depression, LTD)
Glutathione is a small protein molecule composed of the amino acids glutamate, glycine, and cysteine
Shola, D
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