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But cancer biology has made researchers cautious about any intervention that might increase the replicative capacity of somatic cells

One of the approaches increasingly used in clinical weight management is GLP-1 therapy

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While probiotics have a generally favorable safety profile, individual reactions vary

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Importantly, GLP-1 RAs should be prescribed and managed by clinicians experienced in pediatric obesity (e.g., pediatric endocrinologists or obesity specialists) because of dosing complexities and the need for growth monitoring