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Lyophilization removes water, which is the primary medium for chemical degradation through hydrolysis and oxidation

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The pharmacodynamic profile is significantly improved when these phytochemicals are added to nanoformulations because these formulations improve solubility, extend systemic circulation, and enable selective uptake by ovarian tissues [256]

These approaches provide a conceptual framework for future studies aiming to link gut microbiotaderived signals with -cell biology