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Whats the appropriate dose, frequency, duration

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L-arginine might cause additive blood pressure-lowering effects when taken with nitrates (used for angina) or other antihypertensives, though this is not a formal contraindication as with PDE5 inhibitors

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This may help us explain the individual phenotypes of patients with neurological disease and psychiatric disorders and ensure that an optimal balance is achieved between the efficacy and safety of valproates

It's also a usually complicated question to answer in the sense that it depends very heavily on the region, on the product that you're looking at