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These results are relatively similar to those seen with dulaglutide in the AWARD-5 study, which produced reductions of 12.0 mmol/mol (1.1%) and 3.1 kg for HbA 1c and bodyweight, respectively, after 52 weeks of treatment [20]

After this period, any remaining medication in the pen must be discarded, regardless of how much is left

Additionally, patients need to purchase injection supplies such as needles and sharps containers, though these are relatively inexpensive (usually under 10 monthly)

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Soften scars and fibrotic tissue

As such, lifestyle intervention is the recommended first-line treatment, even in the presence of medications for obesity, T2D, and the first liver-targeted drug for MASH, Rezdiffra (resmetirom