abnormal ironsulfur clusters lead to deficiencies in target proteins, including complexes I, II, and III
In clinical trials, patients with type 2 diabetes experienced HbA1c reductions that varied by dose (typically 1.5-2.1%), while weight loss in obesity treatment ranged from 15-20% of baseline body weight at the highest doses
Side effects like nausea or diarrhea may still occur but are often mild and improve as your body adapts
You will lie on your stomach
next steps under evaluation vosoritideVOXZOGO / CNP receptor/NPR-B pathway / Peptide / Skeletal ConditionsHypochondroplasiaPhase 3Positive pivotal data
One phase 3 clinical trial found that survodutide led to an average 12% to 18.7% body weight reduction , depending on dose, in adults with obesity and without diabetes after 76 weeks compared to 5% in the placebo group