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reported in their study that ellagic acid evaded MDR more efficiently than 3,4-Dihydroisocoumarins in drug-resistant cancer cell lines such as HCT-15 (that increases the expression of P-gp), and MCF-7/MX (that raises the expression of BCRP), respectively, at much lower doses than the iso-coumarin derivative [215]

Firstly, resveratrol decreases the expression of genes that are responsible for encoding the drug-metabolizing enzymes and drug transporters like ABC efflux transporters and proteins like MRP1/ABCC1 that contribute to the elimination of cancer drugs and chemoresistance [220, 221]

Glucose-6-phosphate dehydrogenase (G-6-PD) mutations in Mexico: four new G-6-PD variants

Cytoskeletal axis (TB-500): sequesters G-actin to enable rapid polymerization at the migrating leading edge

Many users report benefits such as improved skin tone and brightness, increased energy levels, enhanced detoxification, and overall better health