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In contrast, cell lines expressing GSTP1 exhibited an unmethylated and transcriptionally active promoter thus confirming a relationship between hypermethylation and repression of GSTP1 expression (Karius et al., 2011)

The revealed capacity of DSIP to increase the efficiency of oxidative phosphorylation found in vitro experiments could contribute to understanding pronounced stress protective and antioxidant action of this peptide in vivo

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The cancer cells were preincubated with NAC and subsequently treated with NP4 showed a reduced number of TNF- secreted from the macrophages, suggesting that macrophage activation is associated with the NP4-induced oxidative stress