Employee of AstraZeneca (R.C.L., K.M., S.O., J.C., J.N., J.G., L.J., C.J.R.)
However, they likely act on different stages of the neurogenic process
Plasma GLP-1 concentration peaked earlier and were higher in dumping syndrome patients
Indeed, generating a fusion or conjugation between a peptide and a carrier molecule such as an antibody Fc fragment 23,24 or a full antibody 25,26 is a well described half-life extension strategy to address their rapid clearance from circulation and improve their therapeutic potential
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