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Each category has characteristic pharmacokinetic behavior that is reflected in the half-life column of the peptide half-life chart above

In the STEP (Semaglutide Treatment Effect in People with obesity) programme, participants using higher doses of semaglutide (2.4 mg weekly, marketed as Wegovy) achieved average weight reductions of 12-15% over 68 weeks when combined with lifestyle interventions

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This may include: Review of medication history and dose escalation schedule Dietary assessment and advice from a dietitian Blood tests including amylase, lipase, liver function, and coeliac serology if indicated Consideration of imaging or endoscopy if symptoms suggest structural pathology Patients should never discontinue Ozempic without medical advice (except if pancreatitis is suspected), as abrupt cessation can lead to deterioration in glycaemic control

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