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Insulin resistance is defined physiologically as a state of reduced responsiveness in insulin-targeting tissues to high physiological insulin levels and is considered the pathogenic driver of many modern diseases, including metabolic syndrome, nonalcoholic fatty liver disease (NAFLD), atherosclerosis, and T2DM [1]

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In the case of alliin, the resulting sulfenic acids react with each other to form a thiosulfinate known as allicin (half-life in crushed garlic at 23C is 2.5 days)

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Possible side effects include: Mild injection site discomfort (if administered subcutaneously)

Lee SD, Huang CY, Shu WT, Chen TH, Lin JA, Hsu HH et al (2006) Pro-inflammatory states and IGF-I levels in ischemic heart disease with low or high serum iron