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Rev Invest Clin 72:3805

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Some research suggests that the inflammatory cascade triggered by chronically elevated homocysteine may lower the threshold for anxiety and depressive episodes in susceptible individuals

It also contains the ESSENTIAL ANTIOXIDANT ENZYMES

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These are the different types of potential variations to look for: Homozygous variation You have two copies of the same MTHFR variation (either two variations on 677 or 2 variations on 1298)