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However, any loss of lean mass matters because it can affect physical function, fracture risk and how well the body maintains weight and metabolic health over time

Increasing the dose of a GLP-1 can sometimes enhance weight loss or maintain consistent weight loss, explained Fatima Cody Stanford, MD, an obesity medicine scientist at Massachusetts General Hospital Digestive Healthcare Center in Boston

doi: 10.1002/oby.24336

Some researchers have reported unexpected pregnancies while on tirzepatide, likely because improved metabolic health can restore ovulation in women with weight-related anovulation

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Post-weight loss body contouring requires specialized expertise beyond standard cosmetic procedures