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Initially studied for its role in promoting gut health, researchers discovered its extensive healing benefits beyond the gastrointestinal system

Another clinical trial in the UK found that curcumin supplementation ranging from 0.45 to 3.6 g/day for four months was generally well tolerated by people with advanced colorectal cancer, although two participants experienced diarrhea and another reported nausea (9)

Thus, caspase-8 might be at the crossroads of cell death pathways in erythrocytes like in nucleated cells

While the genetic background of the individual with idiopathic vitiligo strongly influences the disease development preventing a successful recovery, the occupational vitiligo is generally induced by exposure and the return to the skin repigmentation is feasible, once the agent to which the subject is exposed to is removed from the work environment

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Across six clinical trials involving over 900 participants, the side effect profile was described as indistinguishable from placebo