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*Correspondence: Predrag Sikiric, [email protected] This article was submitted to Gastrointestinal and Hepatic Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Due to the expression of DPP4 by, and presentation in the plasma membrane of activated T-cells, endothelial cells, epithelial cells, and fibroblasts, chemokines have a high probability of interacting with the membrane-bound extracellular DDP4

Other sources suggest a range up to 36 months (3 years) when stored under optimal conditions

Once inside, it activates pathways that reinforce cellular resilience and healing

While these therapies are still under investigation, early studies in animal models have shown the potential to slow or even reverse some aspects of aging

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