However, based on patterns seen with tirzepatide and semaglutide, we can estimate that real-world retatrutide results will likely fall 3-5 percentage points below clinical trial averages
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Wang L, Xu R, Kaelber DC, et al
Count to fivethis brief pause ensures the full dose stays under the skin
Those tirzepatide numbers come from SURMOUNT-1, where Jastreboffs team logged large, durable weight loss over 72 weeks in adults with obesity
Mounjaros dosing strategy is straightforward, as it was authorized for adults with obesity or a weight-related comorbidity