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Ang II activates AT1 receptors, which can lead to various effects on vascular cells, including vasoconstriction, cell growth, and the induction of pro-inflammatory cytokines, as well as pro-fibrogenic actions (Silva-Velasco et al., 2024)

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Additionally, a study by Keller et al., 2011

A study of workers (n=117) found that the average peak nighttime melatonin levels for day workers was 15.4 ng/mg creating/hr, and the average peak melatonin for night shift workers was almost 50% less (10.9 ng/mg).[ref] Other sources point to the differences in melatonin due to age

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