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The downstream effects most consistently described in the literature: induction of collagen I and III, elastin, and decorin synthesis (Maquart et al., FEBS Letters , 1988), upregulation of VEGF and basic FGF transcripts, induction of antioxidant defense genes including SOD2 and metallothionein isoforms, and modulation of the MMP-2 and TIMP-1/2 balance toward non-fibrotic remodeling

Rusyniak, D.E

Jan 20, 2026 9 min read READ MORE Fitness GLP-1 and Strength Training: Avoiding a Common Pitfall Losing weight on a GLP-1 medication

Clinical studies have found that GLP-1s can reduce the risk of major cardiovascular events, improve blood sugar control and diabetes prevention, and significantly improve liver health

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