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Data presented is the arithmetic mean of three independent experiments

G6PD deficient populations were relatively more common in the upper provinces of southern Thailand than in the southernmost region

doi: 10.1002/ana.10440

They highlight that inadvertent intravascular injection, high cumulative dosing, and patient factors (extremes of age, cardiac, hepatic, or renal disease, pregnancy) are major contributors, and that bupivacaine carries the greatest cardiotoxic risk

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The peptide also demonstrates anti-inflammatory properties through inhibition of certain cytokine pathways