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conducted a pre-specified cardiovascular meta-analysis that included all seven randomized controlled trials with a duration of at least 26 weeks from the SURPASS trials [61]

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It works through multiple mechanisms, increasing blood vessel formation around follicles, reducing inflammation, stimulating collagen synthesis in the dermal papilla, and blocking 5-alpha reductase, the enzyme that converts testosterone to the follicle-damaging DHT

This cadence mirrors the follow-up structure used in chronic disease management and allows for safe, consistent prescription renewal without unnecessary visits