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Over time, the body burns stored fat for energy, supporting steady weight loss and better blood sugar balance

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Harrison CN, Campbell PJ, Buck G, Wheatley K, East CL, Bareford D, et al

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Experimental studies showing the permissive role of GH/insulin-like growth factor-1 (IGF-I) in carcinogenesis have raised concerns regarding the safety of GH replacement in children and adults who have received treatment for cancer and those with intracranial and pituitary tumors

In the linear mixed effects model, mean weight change at 6 months was 2.9 kg (95% CI, 4.1 to 1.7) and at 12 months was 4.2 kg (95% CI, 5.5 to 2.9)