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The Food and Drug Administration (FDA) has approved Eli Lillys once-daily oral GLP-1 receptor agonist, orforglipron, for adults with obesity, or overweight with weight-related medical problems

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This is because of how the SNAC technology temporarily changes the stomachs pH to allow for absorption

The primary goal of treatment should extend beyond weight loss to encompass the preservation of lean mass, improvement in metabolic health, and long-term prevention of obesity-related complications [7]