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While the systems combined interpretation paradigm (early bacterial growth kinetics + PPT threshold + slope verification) could potentially shorten the detection window compared to absolute reliance on visible growth, the inherent limitations imposed by the slow growth characteristics of such organisms make it difficult to achieve results within just a few hours

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doi: 10.1158/0008-5472.CAN-07-5840

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Buse, MD, PhD, Distinguished Professor of Medicine, Director of the UNC Diabetes Care Center