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Association of antidiabetic therapies with lower extremity amputation, mortality and healthcare cost from a nationwide retrospective cohort study in Taiwan

Glucagon-like peptide-1 receptor agonist based medications (GLP-1s) have transformed the treatment landscape for type 2 diabetes and obesity over the past decade ( 1 , 2 )

Modeling Human BBB in vitro The first in vitro BBB models, published in the 1980s, consisted of cultured monolayers of rodent endothelial cells

However, observed weight gains were marginally lower than those seen with the comparator medications in the clinical studies [54, 55]

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