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Covarrubias, A

In the tubular compartment, trajectory analysis using Palantir, applied to integrated single-cell datasets, reconstructed a pathogenic progression starting from injured proximal tubules (iPT) and advancing through urinary aberrant tubular epithelial cells (aTECs) toward fibroblast fates (Zhang et al., 2025b)

C.HardmanM

Route: Administered subcutaneously or orally (semaglutide)

This biologic behavior (33% metastases) is significantly different from that of bronchial well-differentiated neuroendocrine carcinoma (carcinoid tumor) and suggests that with more adequate study, one or more of these tumors may have been reclassified as more aggressive neoplasms (moderately differentiated neuroendocrine carcinoma)

Reference: Baar MP et al