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For most patients with vitamin B12 deficiency, high-dose oral supplements are as effective as intramuscular injections at raising serum B12 levels and resolving symptoms

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Oral forms (capsules or sprays) are easier to give but have less predictable absorption

A dosage of 3 mg/day did not produce more notable side effects compared to the placebo group (Dalton et al., 2011)

GC-MS determined distribution of urinary equol producers as affected by age, gender, and repeated ingestions of soymilk