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JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles

When all participants were analyzed regardless of treatment adherence, weight reduction trends were consistent with those from the primary analysis, confirming robustness of the findings

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The acute form of the disease is characterized by the sudden onset of cardiac insufficiency, while the chronic form results in moderate-to-severe heart enlargement with varying degrees of cardiac insufficiency (52)