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Another oral, non-peptide GLP-1 RA (lotiglipron) has also been withdrawn from development as in early phase clinical trials resulted in elevated liver enzymes which could indicate liver toxicity [30]

This distinction affects safety, regulation, and side effects

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Large-scale epidemiological studies have estimated that the total (poly)phenol intake in Europe ranges between 584 and 1786 mg/d (Reference Wisnuwardani, De Henauw and Androutsos1,Reference Zamora-Ros, Knaze and Rothwell2)

doi: 10.1016/j.carbpol.2019.115072 90 ZhangZXuSWangYYuYLiFZhuHet al

Hyperglycemia and blood glucose deterioration are risk factors for severe COVID-19 with diabetes: a two-center cohort study