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The usage of GLP-1 in obesity with comorbidity and with some causes of obesity such as PCOS, hypothalamic obesity, and insulin tolerance were studied

Fats cannot be used efficiently as an energy source, which leads to fatigue, decreased performance, triglyceride accumulation and glycogen being depleted more rapidly during exercise

Sex differences in the efficacy of Glucagon-like peptide-1 receptor agonists for weight reduction: a systematic review and meta-analysis

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This variability is typical for supplements, where individual gut microbiome composition, diet, and baseline metabolic health all influence outcomes