Mouse serum analysis Mice were anaesthetized with isoflurane, after which blood was collected via the retro-orbital venous sinus into BD microtainer tubes (BD, 365967)

Anthony Didato, DMD Balanced Aesthetics + Wellness 90% of Serotonin Produced in the Gut Approximately 90% of the body's serotonin the neurotransmitter most associated with mood regulation is produced by enterochromaffin cells Cell (Yano et al., 2015) Gut-Brain Axis Bidirectional Communication The gut-brain axis describes bidirectional signaling between the enteric nervous system and central nervous system via the vagus nerve, immune Annals of Gastroenterology Leaky Gut (Intestinal Permeability) and Systemic Inflammation Increased intestinal permeability allows endotoxins (LPS) to enter the bloodstream, triggering systemic inflammatory cascades linked to anxiety, depression, brain fog, Frontiers in Immunology Overnight Fasting Improves Microbial Balance A 12-14 hour overnight fast improves microbial balance and insulin sensitivity

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These measures generally move together, and reading across all three gives a fuller picture than any single number
When you are exposed to environmental pollutants, processed foods, or alcohol, your liver uses up its glutathione stores to neutralize these threats
According to the 2020 NSDUH, nearly 40% of people ages 12-20 reported drinking alcohol