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The researchers find that use of febuxostat reduces the efflux of many drugs mediated by ABCG2 and prolongs the action time of the drug in the body without increasing the level of UA

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Dosage & Administration Administered as a once-weekly subcutaneous injection, Use exactly as directed by your prescribing provider, Do not increase dose without medical guidance, Inject into abdomen, thigh, or upper arm, Rotate injection sites If a dose is missed: Take within 48 hours when possible, Otherwise resume next scheduled dose Precautions Tell your provider if you: Have diabetes or eye disease, Have kidney or pancreas problems, Take other prescription or OTC medications, Have mental health history including depression, Do not discontinue treatment without consulting your provider

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Note: This article is provided for informational purposes only and does not substitute for professional medical advice.