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Pretreatment with astaxanthin liposomes can reduce ROS generation in corneal epithelial cells and significantly inhibit the expression of the aging-related genes P53, P21, and P16 in in vivo and in vitro DE models [155, 183]

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Most patients notice appetite suppression within 3 to 7 days, but measurable weight loss on the scale typically appears between weeks 2 and 4