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Reactions were initiated by the addition of CDNB, and absorbance changes were recorded for 20 s using a Perkin Elmer LAMBDA 25 UV/VIS Spectrophotometer (Waltham, MA, USA)

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Although these studies are considered long-term randomized controlled trial studies, they still only cover roughly 2-4 years, and patients may have been using GLP-1RA in clinical practice for a very short period of time

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