Kidney disease can affect the ability to metabolize vitamin B12
[11] Serious but uncommon events include immediate-type hypersensitivity with urticaria, bronchospasm, or anaphylaxis, and delayed eosinophilic myositis
The peptide sequence, derived from human growth hormone, appears sufficiently similar to native proteins that the immune system does not mount a response against it
Strong AP, Haeusler S, Weatherall M, Krebs J (2016) Sublingual vitamin B12 compared to intramuscular injection in patients with type 2 diabetes treated with metformin: a randomized trial
And emerging research suggests GIP may have protective effects on brain function and bone density, areas where pure GLP-1 agonists have raised some concerns
The exact dosage is dependent on medical condition, response to the treatment, age, and weight