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George, A., Kaye, S

can destabilize redox homeostasis, contributing to the development of various pathologies such as cancer, cardiovascular disorders, and age-related diseases [46]

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CCL11 enhances excitotoxic neuronal death by producing reactive oxygen species in microglia

Available online at: (Accessed December 19, 2024)

Subsequently, AA-PE and AdAPE are oxidized by 15-lipoxygenase (15-LOX) to produce lipid hydroperoxide, which ultimately leads to ferroptosis (Gao and Jiang, 2018), and further research finds that ferroptosis is initiated by the selective and specific peroxidation of sn2-ETE-PE to sn2-15HpETE-PE by 15-LOX/PEPB1 complex (Kagan et al., 2017