fda approved glp 1 New GLP-1 Pill Foundayo (Orforglipron) Gets Approval for Obesity FDA Ban on Compounded GLP-1

(54) found that administering GIPR antagonist to healthy humans reduced postprandial insulin secretion and increased glucose excursions more than administering GLP-1R antagonist (GLP-1RA), indicating that endogenous GIP may play a more significant role in stimulating insulin secretion and reducing postprandial plasma glucose excursions compared to endogenous GLP-1

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This may reduce the risk for widespread issues ranging from constipation to weight gain

However, women managing both conditions need more frequent monitoring and may need coordinated care between endocrinology and gynecology

doi: 10.1212/WNL.0000000000010245

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