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Those with pre-existing GI conditions, including gastroparesis, inflammatory bowel disease, or chronic pancreatitis, should avoid retatrutide entirely

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Current insight into the cardiovascular biology of GIP is limited, whereas GLP1 reduces major adverse cardiovascular events in humans

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So what follows is a walk through what the in-vitro evidence honestly supports, what it doesnt, and the handful of places where careful researchers still shrug and admit theyre not sure

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