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Nanomedicine 12 , 655664 (2016)

This substantial participant database provides meaningful safety evidence across varied dosing regimens, administration routes (oral and injectable), and treatment durations, making it one of the more extensively studied peptide fragments in human clinical trials

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27 Finally, a 2016 analysis compared apixaban to the other three NOACs and warfarin, concluding that apixaban had the best safety and efficacy profile