This fragmentation leads to high abandonment rates, where up to 64% of patients stop therapy within a year due to unmanaged side effects
Here are 8 potential reasons why not to prescribe Lixisenatide: 1- this is only one small study and only one dose was tested, 2- Lixisenatide is not currently available at pharmacies, 3- the weight loss associated with this GLP-1 is not desirable in many cases of Parkinsons disease where weight loss is an issue, 4- non-motor outcomes did not change as in other trials, and this will need to be better explained
Glutathione seems to remain active in body cells for much longer, protecting them from oxidative stress
Tissue Repair : The peptide accelerates wound healing, collagen formation, and connective tissue repair, which may benefit joints, cartilage, and skin
The peptide PYY 3-36 was used as a positive control
The New England Journal of Medicine, 341, 491-497