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Adverse Reactions The most common adverse reactions (10%) reported in RADICAVA (edaravone)-treated patients and at least 2% more frequently than placebo were contusion (15% vs 9%), gait disturbance (13% vs 9%), and headache (10% vs 6%), respectively

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Levodopa (without Carbidopa) Effect: Pyridoxine (Vitamin B6) may reduce the effectiveness of Levodopa

A few may experience some minor side effects, such as soreness at the injection site, some reddening, or a temporary feeling of heat