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They rely on random cardio

Using GLP-1s for any eating disorders, including anorexia, bulimia or binge eating disorder, is not medically recommended

Tirzepatide is not appropriate for people with certain medical conditions, such as a history of medullary thyroid carcinoma or MEN2, and it must be prescribed after a thorough medical evaluation

10.1056/NEJMoa1607141 120

Drug pricing changes frequently

Circulating plasma GLP-1 levels rise from approximately 510 pmol/L in the fasted state to 1550 pmol/L in the postprandial state, with peak levels depending on meal composition, caloric density, and rate of gastric emptying