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Other PPARA processes were expressed at higher levels in BWS and nonBWS hepatocytes, including the lipoprotein, cholesterol biosynthesis, and inhibition of TG lipases categories (Supplementary Fig
When lipid peroxide generation exceeds the clearance capacity of GPX4, irreversible damage to membrane integrity occurs, culminating in ferroptosis
In cancer cells, high concentration of NO can damage various macromolecules such as nucleic acids and proteins and finally trigger apoptosis