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Numerous studies have confirmed that dysbiosis of the gut microbiota contributes to the multiple hits involved in liver injury

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Moreover, chronic pain itself has been associated with impairments in attention, memory, and other cognitive domains, as documented in clinical literature on pain-related cognitive dysfunction, which may confound the interpretation of neurobehavioral outcomes in these patient populations (Patel et al., 2025)

Activities like mindfulness, meditation, and exercise may help

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