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mTORC1 further supports glycine synthesis by enhancing glycolytic flux and glucose uptake, contributing to a self-reinforcing cycle that sustains collagen production [108, 109]

Looking forward, the integration of complementary technologies bulk, single-cell, spatial, and multi-omics together with computational modeling will be critical for connecting molecular-level discoveries in MuSC biology to systemic physiology and, eventually, to translational interventions for muscle aging

None has been evaluated for safety, quality, or effectiveness

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some references extend to ~16 weeks, followed by a 24 week pause

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