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Understanding the differences between these peptides is crucial for clinicians and researchers alike, as it enables informed decision-making regarding their use in specific clinical contexts

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AcAc is converted in a reversible reaction catalyzed by D--hydroxybutyrate dehydrogenase (BDH1), leading to the formation of BHB, or undergoes non-enzymatic decarboxylation with the formation of acetone (Figure 2) (104, 105)