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Several studies have pointed out that ASD subjects of all ages present nutritional abnormalities and redox imbalances caused by the dysfunctional mitochondria ( Several studies have proposed that ASD may involve different biological profiles, including alterations in redox balance, mitochondrial dysfunction and immune-inflammatory signaling
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Guidelines recommend a daily intake of 400 g of folic acid during the preconception period and during the first trimester of pregnancy to prevent neural tube defects (NTDs) (64)
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